The top 20 US stock market transactions: McDonald's fell more than 5%, and the actual number of infected people in its E. coli infection event should be far more than 49. McDonald's closed down 5.12%, with a transaction volume of 5.559 billion US dollars. On October 22nd local time, the Centers for Disease Control and Prevention (CDC) announced a serious outbreak of E. coli infection related to McDonald's in the United States. At present, 49 people have been infected with the same type of E. coli in 10 states, and 10 people have been hospitalized. One elderly person has died, and one child has been hospitalized due to complications of hemolytic uremic syndrome (HUS). The agency also believes that the actual number of infected people in the McDonald's E. coli infection event should be far more than 49.