[Top 20 US Stock Turnover: Novartis Pharmaceuticals' Stock Price Rises 99%] 20th Place Novartis Pharmaceuticals closed up 98.66%, marking its largest daily increase since its IPO in the United States, with a transaction volume of $1.675 billion. Novartis Pharmaceuticals has announced a multi billion dollar partnership agreement with French pharmaceutical giant Sanofi Aventis. According to the agreement, the two sides will jointly commercialize the COVID-19 vaccine of Novavax Pharmaceuticals from next year, and jointly develop a combined vaccine for coronavirus and influenza.