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On Friday (September 27th) local time, Sanofi and Regeneron Pharmaceuticals both announced on their official websites that their heavyweight drug "Dabitol" was approved in China and the United States on the same day.
According to Sanofi China, Dabitou was approved in China before it was approved in the United States. The official websites of Sanofi and Fosun Pharma also show that although they are both on the same day, the press releases approved in China are released earlier than those approved in the United States.
Source: Sanofi official website

Specifically, the US Food and Drug Administration (FDA) has approved dupilumab injection (trade name "Dupixent") for maintenance therapy of chronic obstructive pulmonary disease (COPD), making it the first drug approved in the United States for the treatment of COPD.
It is understood that COPD is a common lung disease that can cause airflow limitation and respiratory problems, and patients' lungs may be damaged or blocked by phlegm. Symptoms include coughing, sometimes accompanied by phlegm, difficulty breathing, wheezing, and fatigue.
Smoking and air pollution are the most common causes of chronic obstructive pulmonary disease, and patients are at a higher risk of developing other health problems. According to the World Health Organization's 2023 report, COPD is the third leading cause of death worldwide, causing 3.23 million deaths in 2019.
[align center] Source: World Health Organization

Previously, Dupixent has been used globally to treat immune system related diseases such as asthma and eczema. According to a report by Sanofi, the sales of this drug reached 10.72 billion euros (approximately 11.94 billion US dollars) last year.
The company expects that after the approval of COPD indications in China, the sales of this "star drug" will experience a steeper growth. According to data compiled by LSEG, analysts on average expect Dupixent to generate over 21 billion euros in annual revenue by 2030.
In a phase III trial, Dupixent reduced the incidence of moderate or severe COPD exacerbations by 30% and 34%, respectively. BMO Capital Markets analyst Evan Seigerman estimated in May that the drug's peak sales in chronic obstructive pulmonary disease would reach $2.9 billion.
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